Thierry Levade Selected Research

Pyrrolidines

10/2020	Concise asymmetric synthesis of new enantiomeric C-alkyl pyrrolidines acting as pharmacological chaperones against Gaucher disease.
1/2019	Selective Targeting of the Interconversion between Glucosylceramide and Ceramide by Scaffold Tailoring of Iminosugar Inhibitors.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Thierry Levade Research Topics

Disease

34	Neoplasms (Cancer) 10/2021 - 05/2003
22	Melanoma (Melanoma, Malignant) 01/2021 - 06/2003
13	Farber Lipogranulomatosis 01/2020 - 11/2008
7	Gaucher Disease (Gaucher's Disease) 10/2020 - 10/2012
5	Lysosomal Storage Diseases (Lysosomal Storage Disease) 10/2019 - 09/2009
5	Starvation 11/2011 - 03/2006
4	Inflammation (Inflammations) 01/2022 - 11/2009
4	Inborn Genetic Diseases (Disease, Hereditary) 01/2015 - 05/2004
3	Infections 02/2016 - 01/2009
3	Nervous System Diseases (Neurological Disorders) 08/2015 - 09/2009
3	Leukemia 04/2012 - 01/2011
3	Heart Failure 09/2007 - 01/2004
2	Ataxia (Dyssynergia) 01/2022 - 11/2006
2	Mucopolysaccharidoses 01/2022 - 01/2018
2	Niemann-Pick Diseases (Niemann Pick Disease) 10/2021 - 01/2011
2	Skin Neoplasms (Skin Cancer) 11/2020 - 01/2019
2	Type C Niemann-Pick Disease (Niemann Pick Disease, Type C) 01/2017 - 09/2009
2	Fabry Disease (Fabry's Disease) 01/2017 - 06/2009
2	Refsum Disease (Refsum's Disease) 01/2015 - 11/2006
2	Obesity 08/2014 - 02/2012
2	Insulin Resistance 04/2013 - 02/2012
2	Weight Loss (Weight Reduction) 02/2013 - 11/2009
2	Alcoholic Fatty Liver 02/2013 - 11/2009
2	Necrosis 02/2013 - 12/2002
2	Infarction (Infarctions) 10/2012 - 09/2007
2	Lymphoid Leukemia 03/2011 - 01/2011
2	beta-Mannosidosis (beta-Mannosidase Deficiency) 09/2009 - 01/2009
1	Non-alcoholic Fatty Liver Disease 01/2022
1	Mucopolysaccharidosis IV (Morquio Syndrome) 01/2022
1	Fibrosis (Cirrhosis) 01/2022
1	Type B Niemann-Pick Disease 01/2021
1	Nevus (Nevi) 11/2020

Drug/Important Bio-Agent (IBA)

29	CeramidesIBA 10/2021 - 06/2003
28	SphingolipidsIBA 11/2020 - 12/2002
17	EnzymesIBA 01/2021 - 05/2003
14	Acid CeramidaseIBA 01/2020 - 04/2007
8	LipidsIBA 01/2022 - 02/2009
8	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2019 - 12/2002
7	Proteins (Proteins, Gene)FDA Link 01/2018 - 05/2004
6	Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA 01/2021 - 01/2004
6	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 02/2020 - 12/2009
4	SphingomyelinsIBA 10/2021 - 05/2012
4	Glucosylceramidase (Glucocerebrosidase)IBA 02/2020 - 06/2016
4	SphingosineIBA 02/2020 - 05/2003
4	Glucosylceramides (Glucocerebrosides)IBA 02/2020 - 05/2012
4	ceramide glucosyltransferaseIBA 02/2020 - 06/2003
4	sphingosine kinaseIBA 01/2020 - 09/2005
4	AntibodiesIBA 11/2019 - 11/2002
4	CytokinesIBA 01/2017 - 01/2009
3	Choline (Choline Chloride)IBA 01/2022 - 11/2009
3	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2017
3	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 11/2009
3	GangliosidesIBA 10/2019 - 11/2011
3	phosphatidylcholine-ceramide phosphocholine transferaseIBA 01/2019 - 05/2012
3	Lysergic Acid Diethylamide (LSD)IBA 01/2018 - 11/2008
3	Fas Ligand Protein (Fas Ligand)IBA 01/2017 - 04/2009
3	CaspasesIBA 01/2017 - 11/2002
3	HydrolasesIBA 06/2016 - 12/2004
3	CholesterolIBA 01/2014 - 09/2009
3	Triglycerides (Triacylglycerol)IBA 02/2013 - 11/2009
3	LigandsIBA 03/2011 - 01/2003
2	Tumor Necrosis Factor InhibitorsIBA 01/2021 - 11/2019
2	Infliximab (Remicade)FDA Link 01/2021 - 11/2019
2	Fatty Acids (Saturated Fatty Acids)IBA 10/2020 - 02/2012
2	PyrrolidinesIBA 10/2020 - 01/2019
2	Immune Checkpoint InhibitorsIBA 01/2020 - 11/2019
2	AcidsIBA 02/2017 - 01/2004
2	Caspase 9IBA 01/2017 - 04/2012
2	Biological ProductsIBA 01/2017 - 12/2006
2	Phytanic AcidIBA 01/2015 - 11/2006
2	CeramidasesIBA 08/2014 - 08/2011
2	Methionine (L-Methionine)FDA Link 02/2013 - 11/2009
2	GlycosphingolipidsIBA 02/2013 - 09/2009
2	Alanine Transaminase (SGPT)IBA 02/2013 - 11/2009
2	Photosensitizing Agents (Photosensitizers)IBA 03/2011 - 01/2011
2	Plant LectinsIBA 03/2011 - 01/2011
2	PorphyrinsIBA 03/2011 - 01/2011
2	AntigensIBA 03/2011 - 01/2011
2	5- (4- (5- carboxy- 1- butoxy)phenyl)- 10,15,20- tris(4- N- methyl)pyridiniumylporphyrinIBA 03/2011 - 01/2011
2	Polysaccharides (Glycans)IBA 03/2011 - 01/2011
2	LyasesIBA 04/2010 - 12/2009
2	beta-MannosidaseIBA 09/2009 - 01/2009
2	alpha-Galactosidase (Beano)IBA 06/2009 - 01/2006
2	Beclin-1IBA 05/2009 - 03/2006
1	Pharmaceutical PreparationsIBA 01/2022
1	Drinking WaterIBA 01/2022
1	GalactosidasesIBA 01/2022
1	FructoseIBA 01/2022
1	Carbon MonoxideIBA 10/2021
1	Phosphorylcholine (Phosphocholine)IBA 10/2021
1	NivolumabIBA 01/2021
1	IpilimumabIBA 01/2021
1	Interleukin-12 (IL 12)IBA 01/2021
1	Microphthalmia-Associated Transcription FactorIBA 11/2020
1	Monophenol Monooxygenase (Tyrosinase)IBA 11/2020

Therapy/Procedure

11	Therapeutics 01/2021 - 04/2006
6	Drug Therapy (Chemotherapy) 02/2020 - 04/2007
4	Immunotherapy 11/2019 - 10/2018
2	Photochemotherapy (Photodynamic Therapy) 03/2011 - 01/2011
1	Lasers (Laser) 01/2021